All configurationsSome configurationsNoneNot reported by EPA
Configurations by year
2023 Mercedes-Benz CLS-Class
1 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS450 4matic
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
All-Wheel
Yes
Premium
No
2022 Mercedes-Benz CLS-Class
1 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS450 4matic
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2021 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS53 4matic Plus
3.0L 6-cyl hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
CLS450
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS450 4matic
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2020 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS53 4matic Plus
3.0L 6-cyl hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
CLS450
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS450 4matic
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2019 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS53 4matic Plus
3.0L 6-cyl hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
CLS450
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS450 4matic
3.0L 6-cyl turbo hybrid
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2018 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS63 S 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS550
4.7L 8-cyl turbo
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2017 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS63 S 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS550
4.7L 8-cyl turbo
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2016 Mercedes-Benz CLS-Class
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
AMG CLS63 S 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS400
3.0L 6-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Yes
Premium
No
CLS400 4matic
3.0L 6-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS550
4.7L 8-cyl turbo
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
9-speed automatic9-spd
4-Wheel
Yes
Premium
No
2015 Mercedes-Benz CLS-Class
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS400
3.0L 6-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Yes
Premium
No
CLS400 4matic
3.0L 6-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS550
4.7L 8-cyl turbo
9-speed automatic9-spd
Rear-Wheel
Yes
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS63 AMG S 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
2014 Mercedes-Benz CLS-Class
6 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS550
4.7L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Yes
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS63 AMG
5.5L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Yes
Premium
No
CLS63 AMG 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
CLS63 AMG S
5.5L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Yes
Premium
No
CLS63 AMG S 4matic
5.5L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Yes
Premium
No
2013 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS550
4.7L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
No
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
No
Premium
No
CLS63 AMG
5.5L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
No
Premium
No
2012 Mercedes-Benz CLS-Class
3 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS550
4.7L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
CLS550 4matic
4.7L 8-cyl turbo
7-speed automatic7-spd
4-Wheel
Not reported
Premium
No
CLS63 AMG
5.5L 8-cyl turbo
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
2011 Mercedes-Benz CLS-Class
2 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS550
5.5L 8-cyl
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
CLS63 AMG
6.3L 8-cyl
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
2010 Mercedes-Benz CLS-Class
2 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
CLS550
5.5L 8-cyl
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
CLS63 AMG
6.3L 8-cyl
7-speed automatic7-spd
Rear-Wheel
Not reported
Premium
No
Check before you buy or refuel Confirm on the window sticker, owner's manual or with the dealer. Trims and options can differ from the configurations EPA tested.
About premium fuel EPA data shows the fuel a vehicle was tested on. It does not say whether premium is required or only recommended. Your owner's manual or fuel-door label is the authority.
Before using E85 Confirm the vehicle is a flex-fuel vehicle (FFV) in the owner's manual, or look for a yellow gas cap or an "FFV" badge. Not every version of a model is flex-fuel.